The Zika project aims to investigate the association between Zika virus infection and microcephaly and Guillain–Barré syndrome (GBS). Together with the department of immunology, the immune response in infected individuals will be studied, both in single or double infections (Zika and dengue / Zika and chikungunya). In addition, the effect of arbovirus outbreak in general and Zika virus in particular on blood transfusion in Curaçao and the Caribbean will be investigated.